Sophia Herzog Sachs suffered from a severe neurologic disease, called Niemann-Pick Type-A, for which there is no known cure, and which usually leads to death by 2 to 3 years of age. Thanks to the loving care of family, friends and community, Sophia lived a rich and amazing life for over 4 years.
Niemann-Pick disease is characterized by the inability of a specific gene to express correctly and synthesize an essential metabolic enzyme called Acid Sphingomyelinase (ASM).
Music for "Sophia's Garden" was created by translating the genetic instructions from the gene that codes for the synthesis of ASM into information that can be used by various synthesizers and other types of musical instruments. In this way the genetic sequences have become the themes and motifs for the music.
For the final selection of the CD, I recorded the sounds of Sophia's voice so that she could "sing along" with the music. All of the musical sounds and the sound effects on this selection were derived from the recorded sounds of Sophia's voice. These sounds were then correlated to the genetic instructions via the same method as in the other pieces on the CD.
Sophia died on July 25, 2005. In spite of incredible life challenges, Sophia brought an abundance of joy and wisdom to so many who entered her 'garden'.